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Prevotella intermedia infection causing acute and complicated aortitis-A case report
C Boersma1, L M Kampschreur1, H Buter1
1Medical Center Leeuwarden, Henri Dunantweg 2, 8934 AD Leeuwarden, The Netherlands (5).
Introduction:
Aortitis is a general term that refers to all conditions involving an inflammation of the aortic wall. This case report describes the surgical approach of a patient with infectious and symptomatic aortitis caused by the rare vector Prevotella intermedia.
Presentation Of Case:
A 44-year old male patient was admitted with fever and general discomfort after a period of sore throat in a non-teaching hospital. After two weeks he developed acute abdominal and back pain accompanied by sweating and elevated infection parameters. Computed tomography angiography revealed atherosclerotic changes of the infrarenal aorta with a locally contained rupture of the aorta alongside peri-aortal signs of inflammation (and aortitis aspects). An urgent aortic reconstruction was performed according to Nevelsteen. The blood cultures turned out positive for Prevotella intermedia. Postoperatively the patient received antibiotics for six weeks. The patient recovered uneventful from this infection and surgical procedure.
Discussion:
A complicated and acute aortitis is a rare but potentially life-threatening disease. The aetiology can be ordered into two main groups; inflammatory and infectious. Diagnosis is based upon symptoms, biochemical values, microbiological results and imaging modalities. Treatment depends on aetiology and should be discussed in an experienced multidisciplinary setting. Infectious aortitis should be treated with antibiotics for at least six weeks with close monitoring of the patient's clinic and biochemical values, even after surgery.
Conclusion:
Prevotella intermedia is a rare causative agent for aortitis. Acute aortitis is a challenging clinical entity which should be managed in an equipped medical center by an experienced multidisciplinary team.
Insights
This case report details a rare instance of infectious aortitis caused by Prevotella intermedia. Prompt surgical intervention and a six-week antibiotic course led to a successful recovery from this life-threatening condition.
Area of Science:
- Cardiovascular Surgery
- Infectious Diseases
- Vascular Surgery
Background:
- Aortitis encompasses inflammation of the aortic wall, presenting diverse etiologies.
- Infectious aortitis, though rare, poses significant life-threatening risks.
- Prevotella intermedia is an uncommon pathogen implicated in infectious aortitis.
Purpose of the Study:
- To report a case of infectious aortitis caused by Prevotella intermedia.
- To describe the surgical and antibiotic management of this rare condition.
- To highlight the importance of multidisciplinary care in managing acute aortitis.
Main Methods:
- A 44-year-old male presented with symptoms suggestive of aortitis, including fever and abdominal/back pain.
- Computed tomography angiography revealed aortic atherosclerosis, contained rupture, and signs of inflammation.
- Surgical aortic reconstruction was performed, followed by a six-week course of antibiotics targeting Prevotella intermedia.
Main Results:
- Blood cultures confirmed Prevotella intermedia as the causative agent.
- The patient underwent successful aortic reconstruction and recovered uneventfully.
- Postoperative antibiotic therapy was crucial for resolving the infection.
Conclusions:
- Acute aortitis is a complex clinical challenge requiring prompt diagnosis and management.
- Infectious aortitis necessitates aggressive antibiotic treatment (minimum six weeks) and close monitoring.
- Management should occur in specialized centers with experienced multidisciplinary teams.
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