Prevotella intermedia infection causing acute and complicated aortitis-A case report

C Boersma1, L M Kampschreur1, H Buter1

  • 1Medical Center Leeuwarden, Henri Dunantweg 2, 8934 AD Leeuwarden, The Netherlands (5).

Abstract

Insights

This case report details a rare instance of infectious aortitis caused by Prevotella intermedia. Prompt surgical intervention and a six-week antibiotic course led to a successful recovery from this life-threatening condition.

Area of Science:

  • Cardiovascular Surgery
  • Infectious Diseases
  • Vascular Surgery

Background:

  • Aortitis encompasses inflammation of the aortic wall, presenting diverse etiologies.
  • Infectious aortitis, though rare, poses significant life-threatening risks.
  • Prevotella intermedia is an uncommon pathogen implicated in infectious aortitis.

Purpose of the Study:

  • To report a case of infectious aortitis caused by Prevotella intermedia.
  • To describe the surgical and antibiotic management of this rare condition.
  • To highlight the importance of multidisciplinary care in managing acute aortitis.

Main Methods:

  • A 44-year-old male presented with symptoms suggestive of aortitis, including fever and abdominal/back pain.
  • Computed tomography angiography revealed aortic atherosclerosis, contained rupture, and signs of inflammation.
  • Surgical aortic reconstruction was performed, followed by a six-week course of antibiotics targeting Prevotella intermedia.

Main Results:

  • Blood cultures confirmed Prevotella intermedia as the causative agent.
  • The patient underwent successful aortic reconstruction and recovered uneventfully.
  • Postoperative antibiotic therapy was crucial for resolving the infection.

Conclusions:

  • Acute aortitis is a complex clinical challenge requiring prompt diagnosis and management.
  • Infectious aortitis necessitates aggressive antibiotic treatment (minimum six weeks) and close monitoring.
  • Management should occur in specialized centers with experienced multidisciplinary teams.

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