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Updated: Mar 7, 2026
Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
Published on: March 20, 2015
A needle probe to detect surface enhanced Raman scattering (SERS) within solid specimen
Srismrita Basu1, Hsuan-Chao Hou1, Debsmita Biswas1
1Louisiana State University, Baton Rouge, Louisiana 70803, USA.
Abstract:
A needle probe has been developed to obtain surface enhanced Raman scattering data from within a solid specimen located remotely from the spectrometer. It produces the high signal strength of a single mode optical fiber but with a negligible fiber induced background. The observed Raman signal strength is comparable to that obtained with a microscope objective of the same numerical aperture in a conventional spectrometer arrangement and many times larger than that of probes using two fibers.
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