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Related Concept Videos

Feedback Loops01:01

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Proofreading01:31

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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
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Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.
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Updated: Mar 7, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
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Tom Burns1

  • 1Tom Burns, CBE, Professor Emeritus of Social Psychiatry, University of Oxford.

The British Journal of Psychiatry : the Journal of Mental Science
|March 3, 2017
PubMed
Summary

No abstract available in PubMed .

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