Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

656
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
656
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

724
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
724
Cross-reactivity00:42

Cross-reactivity

33.6K
Overview
33.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Population health and implementation outcomes of self-testing for SARS-CoV-2 using antigen detecting diagnostics: a systematic review and meta-analysis.

EClinicalMedicine·2026
Same author

Peak Nasal SARS-CoV-2 and Influenza Viral Loads Relative to Symptom Onset, 2022-2025: Impact of Vaccination and Implications for Multiplexed Testing.

The Journal of infectious diseases·2026
Same author

More than a drop of blood: the paradigm shift of a large-volume capillary sample for point-of-care clinical diagnostics.

Journal of clinical microbiology·2026
Same author

Peak Nasal SARS-CoV-2 and Influenza Viral Loads Relative to Symptom Onset, 2022-2025: Impact of Vaccination and Implications for Multiplexed Testing.

medRxiv : the preprint server for health sciences·2026
Same author

Diagnosis of the first few cases of a novel respiratory pathogen: the FFX-Dx protocol.

Bulletin of the World Health Organization·2026
Same author

Toward diagnostic preparedness: detection of highly pathogenic avian influenza A(H5N1) in contrived nasal swab specimens using rapid antigen and point-of-care molecular tests.

Journal of clinical microbiology·2025

Related Experiment Video

Updated: Mar 7, 2026

Remote Laboratory Management: Respiratory Virus Diagnostics
14:56

Remote Laboratory Management: Respiratory Virus Diagnostics

Published on: April 6, 2019

33.7K

Evaluating Novel Diagnostics in an Outbreak Setting: Lessons Learned from Ebola.

Nira R Pollock1, Betsy Wonderly2

  • 1Department of Laboratory Medicine, Boston Children's Hospital. Harvard Medical School, Boston, Massachusetts, USA nira.pollock@childrens.harvard.edu.

Journal of Clinical Microbiology
|March 3, 2017
PubMed
Summary

The 2014-2016 Ebola outbreak highlighted the need for rapid, point-of-care diagnostics. This study addresses challenges in evaluating novel tests during emergencies and proposes global emergency standards.

Keywords:
EbolaEbola virusdiagnosticdiagnosticsoutbreakpoint of care

More Related Videos

Rapid, Safe, and Simple Manual Bedside Nucleic Acid Extraction for the Detection of Virus in Whole Blood Samples
06:59

Rapid, Safe, and Simple Manual Bedside Nucleic Acid Extraction for the Detection of Virus in Whole Blood Samples

Published on: June 30, 2018

7.8K
Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

17.4K

Related Experiment Videos

Last Updated: Mar 7, 2026

Remote Laboratory Management: Respiratory Virus Diagnostics
14:56

Remote Laboratory Management: Respiratory Virus Diagnostics

Published on: April 6, 2019

33.7K
Rapid, Safe, and Simple Manual Bedside Nucleic Acid Extraction for the Detection of Virus in Whole Blood Samples
06:59

Rapid, Safe, and Simple Manual Bedside Nucleic Acid Extraction for the Detection of Virus in Whole Blood Samples

Published on: June 30, 2018

7.8K
Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
23:56

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

17.4K

Area of Science:

  • Infectious disease diagnostics
  • Public health emergency preparedness

Background:

  • The 2014-2016 Ebola virus disease (EVD) outbreak revealed critical gaps in rapid diagnostic testing access.
  • This led to increased development of point-of-care (POC) diagnostics suitable for less-experienced operators.

Purpose of the Study:

  • To outline the challenges encountered in developing and evaluating novel diagnostics within an emergency setting.
  • To propose the establishment of "global emergency standards" for improved test evaluation during outbreaks.

Main Methods:

  • Review of diagnostic development and evaluation processes during the EVD outbreak.
  • Analysis of limitations in current testing and evaluation frameworks.
  • Formulation of recommendations for future emergency standards.

Main Results:

  • Inadequate access to rapid EVD testing hindered outbreak control.
  • The emergency context necessitated the development of POC diagnostics with simplified operation.
  • Existing evaluation methods proved insufficient for rapid, large-scale deployment.

Conclusions:

  • Novel diagnostic evaluation requires specific standards tailored to emergency conditions.
  • "Global emergency standards" are crucial for ensuring the timely and effective deployment of diagnostics during public health crises.
  • Addressing these challenges will improve response to future infectious disease outbreaks.