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Related Concept Videos

Drugs for Treatment of Constipation-Predominant IBS01:21

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
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Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
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Electroacupuncture for Functional Constipation: A Multicenter, Randomized, Control Trial.

Xiao Wu1, Cuihong Zheng1, Xiaohu Xu2

  • 1Institute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, Hubei 430030, China.

Evidence-Based Complementary and Alternative Medicine : Ecam
|March 3, 2017
PubMed
Summary
This summary is machine-generated.

Electroacupuncture (EA) effectively treats functional constipation (FC), with high current intensity showing superior improvements in quality of life. EA demonstrated better safety and patient satisfaction compared to mosapride.

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Area of Science:

  • Gastroenterology
  • Neurology
  • Integrative Medicine

Background:

  • Functional constipation (FC) is a prevalent gastrointestinal disorder.
  • Current treatments for FC have limitations in efficacy and safety.
  • Electroacupuncture (EA) is an emerging therapeutic option for FC.

Purpose of the Study:

  • To evaluate the efficacy and safety of EA with varying current intensities for FC.
  • To compare EA's effectiveness against mosapride, a common FC medication.
  • To determine if higher EA current intensities yield superior outcomes.

Main Methods:

  • A randomized controlled trial involving patients with FC.
  • Participants were assigned to low current intensity EA (LCI), high current intensity EA (HCI), or mosapride (MC) groups.
  • Primary outcome: ≥3 spontaneous bowel movements (SBMs) weekly for 3 of 4 weeks.

Main Results:

  • HCI group achieved the primary outcome in 66.15% of patients, compared to 53.45% for LCI and 52.24% for MC.
  • EA significantly improved SBM frequency, stool consistency, and reduced straining (p < 0.0001).
  • HCI notably enhanced quality of life and reduced severe constipation more than mosapride (p < 0.05).

Conclusions:

  • EA is a safe and effective treatment for FC at both low and high current intensities.
  • While not superior to mosapride in primary efficacy, EA offers better quality of life and treatment satisfaction.
  • EA exhibited a more favorable safety profile with fewer adverse events than mosapride.