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Related Concept Videos

X-ray Imaging01:24

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German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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Positron Emission Tomography01:29

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
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Magnetic Resonance Imaging01:24

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Computed Tomography01:10

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Updated: Mar 7, 2026

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
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Radio-graphene in Theranostic Perspectives.

Do Won Hwang1,2,3

  • 1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, South Korea.

Nuclear Medicine and Molecular Imaging
|March 3, 2017
PubMed
Summary
This summary is machine-generated.

Radioisotope-labeled graphene, or radio-graphene, offers a promising platform for targeted drug delivery and in vivo evaluation in biomedicine. This review explores its current applications in cancer diagnosis and therapy, paving the way for future clinical translation.

Keywords:
In vivo cancer targetingPET imagingRadio-grapheneTheranostics

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Area of Science:

  • Nanomaterials Science
  • Biomedical Engineering
  • Radiochemistry

Background:

  • Graphene, a 2D-layered nanomaterial, possesses unique physicochemical properties like high surface area, biocompatibility, and mechanical strength.
  • Its potential in biomedical applications, particularly for drug delivery and in vivo evaluation, is rapidly advancing.
  • There is a growing demand for techniques to assess graphene's behavior within living organisms for clinical translation.

Purpose of the Study:

  • To review current bioapplications of radioisotope-labeled graphene (radio-graphene).
  • To highlight the use of radio-graphene in cancer diagnosis and therapy.
  • To provide perspectives on future strategies for extensive bio- or clinical applications of radiolabeled graphene.

Main Methods:

  • Review of existing literature on radiolabeled graphene in biomedicine.
  • Analysis of studies focusing on in vivo evaluation and targeted drug delivery using radio-graphene.
  • Exploration of radio-graphene's role in cancer diagnosis and therapeutic applications.

Main Results:

  • Radio-graphene has been successfully utilized for in vivo tracking and targeted drug delivery.
  • Applications in cancer diagnosis and therapy demonstrate the potential of radio-graphene.
  • Graphene's drug loading capacity makes it a suitable candidate for drug delivery systems.

Conclusions:

  • Radiolabeled graphene is a valuable tool for acquiring in vivo information crucial for targeted drug delivery.
  • Current applications show significant promise for radio-graphene in cancer diagnosis and therapy.
  • Further research and development are essential for the extensive bio- and clinical translation of radio-graphene technologies.