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Updated: Mar 7, 2026

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Unusual Horner's Syndrome in Recurrent Breast Cancer: Evaluation Using 18F-FDG PET/CT
Sohyun Park1,2, Tae Sung Kim1, Seok-Ki Kim1
1Department of Nuclear Medicine, National Cancer Center, Goyang-si, Gyeonggi-do 463-707 Republic of Korea.
Abstract:
18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is a widely used imaging modality in the initial diagnosis of cancer, treatment response evaluation and detection of recurrence. Herein, we present the case of a 39-year-old female who presented right ptosis on the follow-up of breast cancer after surgery. Clinicians suspected Horner's syndrome, and the patient underwent FDG PET/CT for the evaluation of recurrence that could cause Horner's syndrome. FDG PET/CT demonstrated a focal hypermetabolic lesion in the right cervicothoracic junction area, corresponding to the preganglionic cervical sympathetic trunk. A subsequent needle biopsy was done, and the lesion was confirmed as metastatic ductal carcinoma. In this case, we could detect the exact location of the recurring lesion that caused Horner's syndrome using FDG PET/CT.
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