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Updated: Mar 6, 2026

Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions
Published on: January 20, 2022
Sequential Double "Clicks" toward Structurally Well-Defined Heterogeneous N-Glycoclusters: The Importance of Cluster
Liliya Latypova1, Regina Sibgatullina1, Akihiro Ogura2
1Biofunctional Synthetic Chemistry Laboratory RIKEN, Hirosawa Wako-shi, Saitama 351-0198 Japan; Biofunctional Chemistry Laboratory A. Butlerov Institute of Chemistry Kazan Federal University 18 Kremlyovskaya street Kazan 420008 Russia.
Abstract:
Structurally well-defined heterogeneous are prepared on albumin via a double click procedure. The number of glycan molecules present, in addition to the spatial arrangement of glycans in the heterogeneous glycoclusters, plays an important role in the in vivo kinetics and organ-selective accumulation through glycan pattern recognition mechanisms.

