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Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
The vitreomacular interface in different types of age-related macular degeneration
Mohamed Abd ElMonaem El-Hifnawy1, Hisham Ali Ibrahim1, Amir Ramadan Gomaa1
1Ophthalmology Department, Alexandria University Faculty of Medicine, Khartoum Square, Azarita, Alexandria, 21526, Egypt.
Aim:
To evaluate the vitreomacular interface in cases with wet age-related macular degeneration (AMD) and to compare them to eyes with dry AMD and normal eyes.
Methods:
This was a cross-sectional comparative study that included 87 eyes with wet AMD, 42 eyes with dry AMD and 40 eyes without AMD as a control group. Optical coherence tomography (OCT) examination was performed for all patients to assess the vitreomacular interface.
Results:
In the wet AMD group, 34.5% of cases had vitreomacular adhesion (VMA). Only 14.3% of dry AMD cases and 10% of control cases had VMA. There was a significant difference between the control group and the wet AMD group (P=0.004) as well as the dry and wet AMD group (P=0.017). There was also a significant difference between the incidence of VMA in patients with subretinal choroidal neovascularization (CNV, type 1) and intraretinal CNV (type 2 or type 3) (P=0.020).
Conclusion:
There is an association between posterior vitreous attachment and AMD. There is also an increased incidence of VMA with intra-retinal CNV.
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