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Optical coherence tomography (OCT) in retinal angiomatous proliferation (RAP).

R Brancato1, U Introini, L Pierro

  • 1Department of Ophthalmology and Visual Sciences, Scientific Institute H.S. Raffaele, University of M.

European Journal of Ophthalmology
|March 3, 2017
PubMed
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Optical coherence tomography (OCT) effectively diagnoses retinal angiomatous proliferations (RAP) in exudative age-related macular degeneration (AMD). OCT confirms intraretinal localization and exudative changes, complementing other imaging techniques.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Diseases

Background:

  • Exudative age-related macular degeneration (AMD) presents diagnostic challenges.
  • Retinal angiomatous proliferations (RAP) are a specific subtype of wet AMD.
  • Accurate diagnosis is crucial for effective management of AMD subtypes.

Purpose of the Study:

  • To evaluate the diagnostic utility of optical coherence tomography (OCT) for retinal angiomatous proliferations (RAP).
  • To compare OCT findings with fluorescein angiography (FA) and indocyanine green videoangiography (ICGA) in AMD patients with RAP.

Main Methods:

  • OCT cross-sections were obtained from 41 eyes of 39 patients diagnosed with AMD and RAP.
  • RAP presence and location were previously confirmed using FA and ICGA.

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  • OCT imaging focused on detecting angiomatous complexes and associated retinal changes.

    • Main Results:

    • OCT successfully detected RAP in all 41 eyes, appearing as focal hyper-reflecting areas within neuroretinal layers.
    • RAP was frequently located near the retinal pigment epithelium (70.7%).
    • OCT revealed associated findings like serous intraretinal edema (all eyes), serous retinal detachment (31.7%), and pigment epithelium detachment (75.6%).

    Conclusions:

    • OCT findings confirm the intraretinal nature of RAP in exudative AMD.
    • OCT is a valuable tool for diagnosing RAP, providing complementary information to FA and ICGA.
    • The imaging modality highlights significant exudative phenomena associated with RAP.