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Updated: Mar 6, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Type 1 Kounis Syndrome in Patient with Idiopathic Anaphylaxis
Tajda Keber1, Jana Makuc1, Gregor Sekavčnik1
1Department of Internal Medicine, General Hospital Slovenj Gradec, Gosposvetska 1, SI-2380 Slovenj Gradec, Slovenia.
Abstract:
Kounis syndrome represents the concurrence of acute coronary syndromes or anginal pain with allergic, hypersensitivity, and anaphylactic reactions. It can be associated with normal coronary angiogram or preexistent coronary pathology. Idiopathic anaphylaxis is defined as anaphylaxis without any identifiable precipitating agent or event. We present a case of male who experienced attacks of dyspnoea, hypoxemia, hypotension, purple-red skin, and chest pain over several years. He was diagnosed with idiopathic anaphylaxis. Based on the pattern of chest pain of ischemic origin during the attacks he was retrospectively diagnosed with Kounis syndrome.
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