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Updated: Mar 6, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Exploring the usage of a mobile phone application in transplanted patients to encourage medication compliance and
Alana Zanetti-Yabur1, Amanda Rizzo2, Nicole Hayde3
1Montefiore - Einstein Center for Transplantation, Montefiore Medical Center, Bronx, NY, USA.
Background:
Medication non-adherence in transplant patients is a grave problem that results in increased rejection episodes, graft loss and significant morbidity.
Methods:
The efficacy of users and non-users of a mobile phone application (mobile app) in promoting medication adherence was investigated. The Beliefs about Medicine Questionnaire (BMQ) and Morisky Medication Adherence Scale (MMAS-8) were used in these cohorts to assess the predilection for poor adherence. Serum tacrolimus, creatinine levels, and rejection episodes were also recorded. Lastly, the patients were tested on their recall of their immunosuppression.
Results:
Overall, patients had extremely negative beliefs about medication reflected in their tendency toward higher predicted rates of non-adherence. Interestingly, though not significant, app users had higher rates of medication recollection.
Conclusions:
The high-risk nature of this population demands efforts to abrogate non-adherence. Caregivers are charged with the responsibility to offer patients a feasible option to safeguard treatment compliance. Mobile apps are a potentially powerful tool, which can be used to decrease non-adherence.
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