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Supine Breast MRI Using Respiratory Triggering.

Natasja N Y Janssen1, Leon C Ter Beek2, Claudette E Loo2

  • 1Department of Radiation Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, Amsterdam, The Netherlands.

Academic Radiology
|March 4, 2017
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Summary
This summary is machine-generated.

This study evaluates a new technique for breast imaging where patients lie on their backs while the scanner synchronizes with their breathing. This method produces clearer images than traditional techniques, though it requires more time to complete the scan.

Keywords:
Magnetic resonance imagingbreastrespiratory motionsupine position3T MRImotion artifactsradiotherapy planningnavigator-echo

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Area of Science:

  • Diagnostic imaging within medical physics
  • Respiratory-triggered magnetic resonance imaging research within radiology

Background:

Current clinical protocols for breast imaging often rely on prone positioning, which differs significantly from the supine orientation used during radiation therapy. This discrepancy complicates the alignment of diagnostic images with treatment planning. No prior work had resolved how to achieve high-quality supine breast imaging without significant motion degradation. Respiratory motion remains a major hurdle for maintaining image clarity in non-prone positions. That uncertainty drove researchers to investigate navigator-echo synchronization as a potential solution for motion suppression. Prior research has shown that standard supine scans suffer from substantial artifacts caused by chest wall movement. This gap motivated the development of a specialized acquisition sequence to stabilize the breast tissue. The current investigation addresses whether this approach can provide diagnostic-grade results comparable to established prone methods.

Purpose Of The Study:

The study aims to evaluate if navigator-echo respiratory-triggered acquisition can produce high-quality supine breast images. Researchers sought to determine if this method could overcome motion artifacts that typically degrade supine scans. The motivation stems from the need to align diagnostic imaging with the patient positioning used during radiotherapy. Current prone imaging protocols often create discrepancies when compared to the supine setup required for treatment. This investigation addresses the technical challenge of stabilizing breast tissue while the patient breathes freely. By comparing triggered supine scans to both non-triggered supine and conventional prone methods, the team assessed the feasibility of this approach. The primary goal was to establish whether the benefits of improved image quality justify the extended scan time. This work provides a foundation for optimizing clinical workflows where anatomical consistency is paramount.

Main Methods:

The review approach involved a comparative analysis of two distinct patient groups to validate the imaging technique. Researchers recruited ten volunteers for each cohort, including one patient, to test the protocol at a field strength of 3T. A 32-channel thorax coil served as the primary tool for data collection, placed over a cover to prevent tissue distortion. The team compared the new supine triggered sequence against both supine non-triggered scans and conventional prone imaging. Visual examinations assessed qualitative parameters, while quantitative analysis focused on signal-to-noise ratio, contrast-to-noise ratio, and image sharpness. Investigators recorded the total time required for each acquisition to determine the efficiency of the synchronization process. Statistical tests evaluated the significance of differences between the triggered and non-triggered datasets. This rigorous design ensured that the performance of the navigator-echo method was thoroughly benchmarked against standard clinical practices.

Main Results:

Key findings from the literature demonstrate that the triggered supine method significantly enhances image quality metrics. In the first group, signal-to-noise ratios improved from a median of 11.5 to 38.1 with the new technique. Contrast-to-noise ratios similarly rose from 7.3 to 32.8, indicating superior tissue differentiation. All qualitative parameters showed statistically significant improvements compared to non-triggered supine scans. When compared to prone imaging, the triggered supine approach yielded signal-to-noise ratios of 36.2 versus 14.7. Contrast-to-noise ratios also improved from 12.6 in the prone group to 32.7 in the triggered supine group. Image sharpness remained comparable between the prone and triggered supine methods, with values of 0.10 cm and 0.11 cm. The primary trade-off identified was an increase in average acquisition time to 306 seconds.

Conclusions:

The authors propose that high-quality supine breast imaging is feasible using respiratory-triggered sequences. This approach allows for patient positioning that closely matches the setup required for subsequent radiotherapy. The researchers suggest that image clarity significantly exceeds that of non-triggered supine scans. Synthesis and implications indicate that signal-to-noise ratios and contrast-to-noise ratios show marked improvements over traditional prone imaging. The study demonstrates that these gains occur despite a notable extension in total scan duration. Clinicians should weigh the benefit of enhanced diagnostic quality against the longer time required for data collection. The findings support the integration of this technique when precise anatomical alignment between imaging and treatment is necessary. Future clinical workflows might benefit from this synchronization to reduce discrepancies in patient positioning.

The researchers propose that navigator-echo synchronization mitigates breathing-induced motion. This mechanism significantly enhances signal-to-noise and contrast-to-noise ratios compared to non-triggered supine imaging, which typically suffers from severe artifacts.

A 32-channel thorax coil was utilized in this study. This hardware was positioned atop a protective cover to minimize breast deformation, ensuring the tissue maintained a natural shape during the supine acquisition.

The authors state that respiratory triggering is necessary to counteract motion artifacts inherent in supine positioning. Without this synchronization, the chest wall movement during breathing obscures diagnostic details, making high-quality imaging difficult to achieve.

The study utilized quantitative metrics, including signal-to-noise ratio, contrast-to-noise ratio, and image sharpness. These values provided objective data to compare the performance of the triggered supine approach against standard prone and non-triggered supine protocols.

The researchers measured total acquisition time, which increased from 56.5 seconds in non-triggered scans to an average of 306 seconds with the triggered method. This duration varied between 120 and 540 seconds depending on the individual.

The authors suggest that this technique allows for imaging in a position identical to subsequent treatment. This alignment reduces errors in radiotherapy planning, providing a more accurate representation of the target area compared to prone scans.