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Vitamin D and muscle trophicity
Carla Domingues-Faria1, Yves Boirie, Stéphane Walrand
1aUnité de Nutrition Humaine, UMR 1019 INRA UCA, Equipe ASMS, CRNH Auvergne bUniversité Clermont Auvergne cService de Nutrition Clinique, CHU Clermont-Ferrand, France.
Vitamin D is crucial for muscle health, impacting mass and strength. Supplementation may improve muscle function, especially in deficient individuals, highlighting its role in muscle repair and development.
Area of Science:
- Endocrinology
- Muscle Physiology
- Nutritional Science
Background:
- Vitamin D deficiency is linked to decreased muscle mass and strength.
- Emerging research highlights vitamin D's role in muscle development and repair processes.
Purpose of the Study:
- To review recent scientific findings on vitamin D's role in skeletal muscle trophicity.
- To explore vitamin D's impact on muscle cell proliferation, differentiation, and metabolism.
Main Methods:
- Review of recent scientific literature and investigations.
- Analysis of studies examining vitamin D's effects on muscle cell behavior and function.
Main Results:
- Vitamin D deficiency correlates with reduced muscle mass and strength.
- Vitamin D influences skeletal muscle cell proliferation, differentiation, and metabolism, including protein synthesis and mitochondrial function.
- Recent studies indicate a genetic contribution of vitamin D to muscle functioning.
Conclusions:
- Vitamin D plays a significant role in maintaining muscle health, mass, and function.
- Its 'trophic' properties are particularly relevant for the elderly, athletes, and individuals with chronic diseases.
- Addressing vitamin D deficiency is important for preserving muscle function across various populations.
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