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Effectiveness of a 16-Week Multimodal Exercise Program on Individuals With Dementia: Study Protocol for a Multicenter
Sandra Trautwein1, Andrea Scharpf1, Bettina Barisch-Fritz1
1Institute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.
JMIR Research Protocols
|March 5, 2017
Summary
This study investigates a multimodal exercise program (MEP) for individuals with dementia (IWD), aiming to improve their motor and cognitive skills. Findings will enhance evidence for physical activity benefits in IWD.
Area of Science:
- Gerontology
- Neurology
- Exercise Science
Background:
- Dementia prevalence is rising, posing societal and economic challenges.
- Physical activity shows potential for improving motor and cognitive skills in individuals with dementia (IWD).
- Existing evidence is limited by methodological issues and a lack of dementia-specific interventions.
Purpose of the Study:
- To evaluate the effectiveness of a novel multimodal exercise program (MEP) for IWD.
- To assess MEP's impact on motor and cognitive functions in a high-quality multicenter trial.
Main Methods:
- A multicenter randomized controlled trial involving 405 participants (mild to moderate dementia, aged 65+).
- A 16-week ritualized MEP specifically designed for IWD.
- Assessment of primary outcomes (balance, mobility, gait) and secondary outcomes (strength, function, ADLs, cognition).
Main Results:
- Enrollment commenced in May 2015, with postassessments planned for early 2017.
- Study results are anticipated in the first half of 2017.
Conclusions:
- This study will strengthen the evidence base for physical activity's role in managing dementia symptoms.
- The dementia-specific, combined motor-cognitive MEP and rigorous methodology offer significant advancements.
- Findings are crucial for addressing motor and cognitive impairments in IWD with limited physical activity.

