Related Experiment Video
Updated: Mar 6, 2026

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
Medication-Assisted Treatment for Adolescents in Specialty Treatment for Opioid Use Disorder
Kenneth A Feder1, Noa Krawczyk1, Brendan Saloner1
1Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
Purpose:
The American Academy of Pediatrics recently recommended that pediatricians consider medication-assisted treatment (MAT) for adolescents with severe opioid use disorders. Little is known about adolescents' current use of MAT.
Methods:
We use data on episodes of specialty treatment for heroin or opioid use (n = 139,092) from a database of publicly funded treatment programs in the U.S. We compare the proportions of adolescents and adults who received MAT, first using unadjusted comparison of proportions, then using logistic regression to adjust for potential confounders.
Results:
Only 2.4% (95% confidence interval [CI], 1.4%-3.7%) of adolescents in treatment for heroin received MAT, as compared to 26.3% (95% CI, 26.0%-26.6%) of adults. Only .4% (95% CI, .2%-.7%) of adolescents in treatment for prescription opioids received MAT, as compared to 12.0% (95% CI, 11.7%-12.2%) of adults. Regression-adjusted results were qualitatively similar.
Conclusions:
Regulatory changes and expansions of Medicaid/CHIP coverage for MAT may be needed to improve MAT access.
Related Concept Videos
Drug Therapy
Antianxiety Medications
Pharmaceutical Poisoning: Treatment Strategies
Antidepressant Drugs: MAOIs and Other Agents
Drug Abuse and Addiction: Pharmacological Phenomena
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...

