Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

92
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
92
Allergic Reactions02:06

Allergic Reactions

33.1K
Overview
33.1K
Allergic Drug Reactions01:27

Allergic Drug Reactions

1.5K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.5K
Cross-reactivity00:42

Cross-reactivity

33.6K
Overview
33.6K
Taste Buds and Receptors01:20

Taste Buds and Receptors

5.6K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
5.6K
Hypersensitivities01:30

Hypersensitivities

8.0K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
8.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterisation of Allergen Profiles in Commercial Egg Products to Inform Oral Immunotherapy Strategies in Egg Allergy.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2026
Same author

Egg Allergy Prevalence Before and After Guidelines for Earlier Egg Introduction.

JAMA pediatrics·2026
Same author

Correlation and Agreement Between Parent-Report and Self-Report Food Allergy Quality of Life Questionnaires After Oral Immunotherapy.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2026
Same author

Timing of Exposure to Cow's Milk Formula and Risk of Developing Cow's Milk Allergy and Sensitization in the HealthNuts Study.

The journal of allergy and clinical immunology. In practice·2026
Same author

Cost-Effectiveness of Oral Immunotherapy Treatments vs No Treatment for Peanut Allergy in Children.

JAMA network open·2026
Same author

Meta-analysis of genome-wide association studies of food allergy and IgE sensitization.

The Journal of allergy and clinical immunology·2026
Same journal

The paradox of peer review: protecting science or policing thought?

Internal medicine journal·2026
Same journal

Immune-related pancytopenia in pregnancy.

Internal medicine journal·2026
Same journal

Crossover effect: causal machine learning reveals opposing mortality responses to mean arterial pressure targets among phenotypically distinct hypertensive patients with septic shock.

Internal medicine journal·2026
Same journal

Clinicopathological findings, correlations and outcomes in patients with renal disease and living with antiretroviral-treated human immunodeficiency virus infection.

Internal medicine journal·2026
Same journal

Approach to thyroid disorders associated with immune checkpoint inhibitors and tyrosine kinase inhibitors.

Internal medicine journal·2026
Same journal

A scoping review of specialist hypertension clinics.

Internal medicine journal·2026
See all related articles

Related Experiment Video

Updated: Mar 6, 2026

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.7K

Food allergy: is prevalence increasing?

Mimi L K Tang1,2,3, Raymond J Mullins4,5

  • 1Allergy and Immune Disorders, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.

Internal Medicine Journal
|March 6, 2017
PubMed
Summary
This summary is machine-generated.

The prevalence of food allergy is rising globally, especially in Western nations. This trend is expected to continue due to lifestyle changes and the lack of effective treatments for food allergies.

Keywords:
anaphylaxisfood allergyprevalence

More Related Videos

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

17.0K
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.8K

Related Experiment Videos

Last Updated: Mar 6, 2026

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.7K
Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

17.0K
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.8K

Area of Science:

  • Immunology
  • Epidemiology
  • Public Health

Background:

  • The increasing prevalence of food allergy is a growing public health concern, particularly in Westernized countries.
  • High-quality evidence confirming this rise is limited due to the challenges of large-scale food challenges.
  • Surrogate markers suggest a significant increase in food allergy cases.

Purpose of the Study:

  • To examine the evidence for the increasing prevalence of food allergy.
  • To explore factors contributing to the rise in food allergy, including ethnicity and lifestyle.
  • To predict future trends in food allergy prevalence.

Main Methods:

  • Analysis of nationwide hospital admission data for food anaphylaxis.
  • Review of clinical history and allergen-specific IgE (sIgE) measurements in population-based cohorts.
  • Examination of epidemiological data on food allergy risk across different ethnicities and environments.

Main Results:

  • Consistent evidence indicates a rising prevalence of food allergy in Western countries like the UK, US, and Australia.
  • Children of East Asian or African ethnicity raised in Western environments show a higher risk of food allergy.
  • Mathematical modeling predicts a continued increase in food allergy prevalence in the short to medium term.

Conclusions:

  • Food allergy prevalence is increasing, driven by Westernized lifestyles and dietary changes.
  • Ethnic and environmental factors play a significant role in food allergy development.
  • Without effective treatments, the rising trend in food allergy is likely to persist.