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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
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Clomiphene citrate-induced visual hallucinations: a case report.
Ramesh Venkatesh1, Gaganjeet Singh Gujral2, Prachi Gurav2
1Department of Retina and Vitreous, Shroff's Charity Eye Hospital, 5027, Kedarnath Road, Daryaganj, New Delhi, 110002, India. vramesh80@yahoo.com.
Journal of Medical Case Reports
|March 7, 2017
Summary
Clomiphene citrate, a common infertility treatment, can cause rare visual disturbances called illusory palinopsias. These persistent afterimages may continue even after medication cessation, requiring patient and physician awareness.
Area of Science:
- Reproductive Endocrinology
- Ophthalmology
- Pharmacology
Background:
- Polycystic ovary syndrome (PCOS) is a leading cause of anovulation and infertility.
- Clomiphene citrate is a standard first-line ovulation induction therapy for PCOS.
- This medication is associated with potential systemic and ocular side effects.
Observation:
- A case study involving a 30-year-old woman with PCOS treated with clomiphene citrate.
- The patient experienced persistent visual afterimages (illusory palinopsias) starting on day four of treatment.
- Symptoms recurred in a subsequent cycle and persisted for over a year after discontinuing the drug.
Findings:
- Clomiphene citrate can induce illusory palinopsias, a rare ocular side effect.
- These visual disturbances can be persistent, lasting beyond the treatment period.
- The condition is infrequently recognized by gynecologists and ophthalmologists.
Implications:
- Highlights a rare but persistent ocular side effect of clomiphene citrate.
- Emphasizes the importance of informing patients about potential visual side effects.
- Suggests increased vigilance among healthcare providers managing infertility treatments for PCOS.
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