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[Hyperimmunoglobulin treatment in CMV infections following heart transplantation]
J Cremer1, H J Schäfers, T Wahlers
1Klinik für Thorax, Herz- und Gefässchirurgie, Medizinischen Hochschule Hannover.
Clinically manifest cytomegalovirus (CMV) infections, with and without pulmonary involvement, occurred in two patients after heart transplantation. The diagnosis was confirmed immunologically. After administration of CMV hyperimmunoglobulin and prophylactic antibiotics and a reduction of immunosuppressives, rapid clinical improvement ensued so that both patients were discharged from hospital after seven and ten days, respectively.
Clinically manifest cytomegalovirus (CMV) infections, with and without pulmonary involvement, occurred in two patients after heart transplantation. The diagnosis was confirmed immunologically. After administration of CMV hyperimmunoglobulin and prophylactic antibiotics and a reduction of immunosuppressives, rapid clinical improvement ensued so that both patients were discharged from hospital after seven and ten days, respectively.