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Updated: Mar 6, 2026

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
Published on: October 15, 2019
Beyond Hygiene: Commensal Microbiota and Allergic Diseases
Sung-Wook Hong1, Kwang Soon Kim1, Charles D Surh2
1Academy of Immunology and Microbiology, Institute for Basic Science, Pohang University of Science and Technology, Pohang 37673, Korea.
Abstract:
Complex communities of microorganisms, termed commensal microbiota, inhabit mucosal surfaces and profoundly influence host physiology as well as occurrence of allergic diseases. Perturbing factors such as the mode of delivery, dietary fibers and antibiotics can influence allergic diseases by altering commensal microbiota in affected tissues as well as in intestine. Here, we review current findings on the relationship between commensal microbiota and allergic diseases, and discuss the underlying mechanisms that contribute to the regulation of allergic responses by commensal microbiota.
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