A case report of a renal diffuse B-cell lymphoma

Area of Science:

• Oncology
• Pathology
• Radiology

Background:

• Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma globally.
• Primary retroperitoneal lymphomas are rare, but DLBCL is the most frequent subtype.
• Retroperitoneal masses often present with nonspecific symptoms, complicating diagnosis.

Observation:

• This case study focuses on a rare presentation of DLBCL originating in the retroperitoneum.
• The patient exhibited nonspecific symptoms common to retroperitoneal masses.
• Radiographic assessment and biopsy were crucial for diagnosis.

Findings:

• The study details the clinical presentation and imaging characteristics of primary retroperitoneal DLBCL.
• It emphasizes the importance of considering lymphoma in the differential diagnosis of retroperitoneal masses.
• Diagnostic challenges include nonspecific clinical and laboratory findings.

Implications:

• Early recognition and diagnosis of primary retroperitoneal DLBCL are essential for timely treatment.
• Radiologists and clinicians should include DLBCL in the differential diagnosis for unexplained retroperitoneal masses.
• This case contributes to the literature on a rare but significant oncologic presentation.