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Updated: Mar 6, 2026

Rapid Magnetic-microbead Method for Efficient Purification of Low-density Neutrophils
Published on: November 11, 2025
[Leukopenia with unclear fever]
S Mayer1, T Kündiger2, H Schrader2
1Medizinische Klinik und Funktionsdiagnostik, Endoskopie, Sana Krankenhaus Gerresheim, Sana Kliniken Düsseldorf GmbH, Gräulinger Str. 120, 40625, Düsseldorf, Deutschland. SabineTheresia.Mayer@Sana.de.
Abstract:
We report on a 77-year-old male patient with neutropenic fever as a result of a newly diagnosed agranulocytosis. The patient was taking metamizole, which is a well known cause of agranulocytosis. The diagnosis of metamizole-induced agranulocytosis as an underestimated side-effect of metamizole could be confirmed by a bone marrow biopsy. The bone marrow and the blood count recovered completely after stopping the therapy with metamizole and administration of granulocyte colony-stimulating factor (G-CSF).
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