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Updated: Mar 6, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
39.6K
Photochemotherapy For Psoria-sis
Indian Journal of Dermatology, Venereology and Leprology
|March 8, 2017
Summary
Photochemotherapy using psoralen and ultraviolet radiation (PUV) effectively treated 50 psoriasis patients. Complete lesion clearance was achieved in all patients within 45 days, demonstrating PUV
Area of Science:
- Dermatology
- Photobiology
- Photomedicine
Background:
- Psoriasis is a chronic inflammatory skin condition.
- Current treatments have limitations.
- Photochemotherapy offers a potential therapeutic avenue.
Purpose of the Study:
- To evaluate the efficacy and safety of psoralen and ultraviolet radiation (PUV) for psoriasis treatment.
- To analyze treatment outcomes in a cohort of psoriatic patients.
Main Methods:
- Treatment involved 50 patients with psoriasis.
- Administration of psoralen followed by exposure to ultraviolet radiation (UVR).
- Data analysis of lesion clearance and treatment duration.
Main Results:
- No patients were resistant to PUV treatment.
- Complete lesion clearance observed in 22% by day 16, 96% by day 40, and 100% by day 45.
- The treatment demonstrated a high success rate across the patient cohort.
Conclusions:
- Photochemotherapy with psoralen and ultraviolet radiation is a safe and effective treatment for psoriasis.
- Conventional UV radiation therapy lamps can be utilized for this treatment.
- PUV therapy offers a viable option for managing psoriasis.
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