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The nucleotide sequence of human rhinovirus 1B: molecular relationships within the rhinovirus genus
P J Hughes1, C North, C H Jellis
1Department of Biology, University of Essex, Colchester, U.K.
The Journal of General Virology
|January 1, 1988
Abstract:
We have determined the complete nucleotide sequence of human rhinovirus 1B and made comparisons with other rhinoviruses. Extensive homology was found with serotypes 2 and 89 but the similarity to serotype 14 was considerably less. Rhinovirus-specific characteristics have been noted, in particular the length of the 5' non-coding region and the pattern of codon usage, and these may be sufficient to define the rhinoviruses as a distinct genus rather than being considered as members of the enteroviruses as has been suggested previously.