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[Changes in the masticatory system in myasthenia gravis].

J Komári, M Klein, A Szobor

    Schweizerische Monatsschrift Fur Zahnheilkunde = Revue Mensuelle Suisse D'Odonto-Stomatologie
    |November 1, 1978
    PubMed
    Summary

    Myasthenia gravis, a condition causing muscle hypofunction, leads to motor dyscoordination and dental caries. This muscle weakness can also cause temporomandibular joint damage, but Tensilon therapy can help diagnose it.

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    Area of Science:

    • Neurology
    • Dentistry
    • Rheumatology

    Background:

    • Myasthenia gravis is characterized by muscle hypofunction and motor dyscoordination.
    • The oral health implications of myasthenia gravis, particularly concerning periodontal health and caries, require further investigation.
    • Temporomandibular joint (TMJ) damage is a potential consequence of the motor dyscoordination associated with myasthenia gravis.

    Purpose of the Study:

    • To examine the oral health consequences of myasthenia gravis in a patient cohort.
    • To investigate the relationship between muscle hypofunction, motor dyscoordination, and dental caries.
    • To assess the diagnostic utility of Tensilon therapy in evaluating TMJ function in myasthenia gravis patients.

    Main Methods:

    • A cohort of 106 patients diagnosed with myasthenia gravis was studied.
    • Dental caries intensity and periodontal status were assessed.
    • TMJ function, including mouth opening and masticatory force, was evaluated before and after Tensilon administration.

    Main Results:

    • Muscle hypofunction in myasthenia gravis did not directly correlate with periodontal issues.
    • A significant increase in dental caries intensity was observed in patients with myasthenia gravis.
    • Tensilon therapy demonstrated a characteristic increase in mouth opening and masticatory force, proving useful for diagnosis.

    Conclusions:

    • Myasthenia gravis is associated with increased dental caries risk, despite no direct impact on periodontal health.
    • Motor dyscoordination resulting from muscle hypofunction can lead to TMJ damage.
    • Tensilon-induced improvements in jaw function serve as a valuable diagnostic marker for myasthenia gravis.

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