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Follicular Porokeratosis, a Porokeratosis Variant
1*Department of Dermatopathology, Pathlab Bay of Plenty, Tauranga, New Zealand; †Skin Dermatology Institute, Tauranga, New Zealand; and ‡Department of Pathology and Molecular Medicine, University of Auckland.
Follicular porokeratosis, a rare variant of abnormal skin keratinization, is now considered an anatomic site variation, not a distinct condition. This finding aids in diagnosing papular keratotic eruptions.
Area of Science:
- Dermatology
- Histopathology
- Keratinization Disorders
Background:
- Porokeratosis encompasses various clinical and histologic forms stemming from abnormal keratinization.
- Follicular involvement in porokeratosis is rarely documented and has been hypothesized to represent a unique entity.
Observation:
- This study details a case of disseminated superficial actinic porokeratosis exhibiting prominent folliculocentric keratosis.
- Histopathological examination revealed the presence of follicular cornoid lamellae.
Findings:
- The observed follicular cornoid lamellae support the classification of follicular porokeratosis as an anatomic site variant of porokeratosis.
- This variant should be considered in the differential diagnosis of discrete papular keratotic eruptions.
Implications:
- Recognizing follicular porokeratosis as a variant refines diagnostic criteria for porokeratosis.
- Increased awareness of this variant can improve clinical recognition and management of related skin conditions.
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