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Selective digestive decontamination in critically ill children: A survey of Canadian providers
Srinivas Murthy1, Nazima Pathan2, Brian H Cuthbertson3
1University of British Columbia, Canada.
Insights
Selective digestive decontamination (SDD) is not routinely used in Canadian pediatric hospitals due to limited pediatric evidence. Further research on SDD facilitators, barriers, and acceptability is needed before pediatric implementation.
Area of Science:
- Pediatric critical care medicine
- Infectious disease prevention
- Antibiotic stewardship
Background:
- Selective digestive decontamination (SDD) uses antibiotics to prevent hospital-acquired infections in mechanically ventilated children.
- Evidence for SDD is strong in adults but limited in pediatric populations.
- Current use of SDD among North American pediatric physicians is unknown.
Purpose of the Study:
- To assess the current utilization and perceptions of SDD among pediatric healthcare providers in Canada.
- To identify barriers and facilitators to SDD implementation in pediatric critical care settings.
Main Methods:
- An electronic survey was distributed to pediatric critical care and infectious disease specialists in Canada.
- Survey questions covered current institutional practices, knowledge of SDD evidence, and perceived risks and benefits.
- Descriptive statistics were used to analyze the survey data.
Main Results:
- Only 35% of surveyed providers responded, with no Canadian hospitals routinely using SDD.
- A majority (74%) held neutral opinions on SDD, citing concerns about antibiotic resistance and the intravenous component.
- Most respondents emphasized the need for pediatric-specific evidence before considering SDD adoption.
Conclusions:
- There is currently limited knowledge and no routine use of SDD for hospital-acquired infection prevention in Canadian pediatric settings.
- Pediatric providers require more evidence specific to their patient population before considering SDD.
- Future research should explore the facilitators, barriers, and acceptability of SDD in pediatric practice.
Background:
Selective digestive decontamination of the digestive tract involves the routine administration of oral, gastric, and intravenous antibiotics to mechanically ventilated children to prevent hospital-acquired infections. It has a strong evidence base in adults, with limited pediatric evidence. Current utilization of this intervention among pediatric physicians in North America is unknown.
Methods:
An electronic survey administered to pediatric critical care and pediatric infectious disease providers in Canada. Participants were surveyed on current institutional practices, their current knowledge of the evidence base, and perceptions of the risks and benefits of the intervention. Descriptive statistics were utilized.
Results:
50 out of 143 (35%) surveyed responded. No hospital in Canada routinely performs SDD and the majority of respondents (74%) have neutral opinions on the subject of SDD. There was concern for increasing antibiotic resistance (43%) and some disagreement with the intravenous component of SDD (46%). The majority of respondents stated a need for pediatric-specific evidence before integrating SDD into their practice, even if further, large adult RCTs were performed.
Conclusion:
Among surveyed providers, there is little knowledge and no use of selective digestive decontamination for the prevention of hospital-acquired infections. Before interventional studies are performed in pediatric practice, there is a need for study of facilitators, barriers and acceptability of SDD in practice.
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