Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Testing stimulus protocols in retinal-prosthesis patients.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2017
Same author

Evaluation of Effects of Electrical Stimulation in the Retina with Optical Coherence Tomography.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2017
Same author

On the thermal elevation of a 60-electrode epiretinal prosthesis for the blind.

IEEE transactions on biomedical circuits and systems·2013
Same author

Elastic and viscoelastic characterization of agar.

Journal of the mechanical behavior of biomedical materials·2012
Same author

Interphase gap decreases electrical stimulation threshold of retinal ganglion cells.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2012
Same author

Response to 'technology for mobility in SCI ten years from now'.

Spinal cord·2012
Same journal

Analysis of End-Tidal CO2 Variability During Plateau Waves Episodes: An Information Theoretic Approach<sup></sup>.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

AI and Tomosynthesis for Breast Cancer Molecular Subtyping: A step toward precision medicine<sup></sup>.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Towards Sustainable Protein Recovery from Biological Waste: Assessing Polyethersulfone-based Microfiltration.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Analysis of the cardiovascular response to standardized polymicrobial peritonitis experimental model.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

Automated Wrist Ultrasound Image Bone Enhancement and Segmentation Using Deep Learning.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same journal

A Deep Learning approach for Depressive Symptoms assessment in Parkinson's disease patients using facial videos.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
See all related articles

Related Experiment Video

Updated: Mar 6, 2026

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
10:52

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

Published on: October 2, 2015

20.7K

Improved electrode material for deep brain stimulation.

A Petrossians, J J Whalen, J D Weiland

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |March 9, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Researchers developed a new platinum-iridium alloy coating for deep brain stimulation (DBS) electrodes. This innovation improves electrical properties and durability for smaller, more effective neuromodulation devices.

    More Related Videos

    A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes
    09:27

    A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes

    Published on: March 3, 2014

    14.0K
    Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
    14:14

    Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

    Published on: August 12, 2018

    9.4K

    Related Experiment Videos

    Last Updated: Mar 6, 2026

    Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
    10:52

    Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

    Published on: October 2, 2015

    20.7K
    A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes
    09:27

    A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes

    Published on: March 3, 2014

    14.0K
    Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models
    14:14

    Targeting Neuronal Fiber Tracts for Deep Brain Stimulation Therapy Using Interactive, Patient-Specific Models

    Published on: August 12, 2018

    9.4K

    Area of Science:

    • Biomedical Engineering
    • Neuroscience
    • Materials Science

    Background:

    • Deep brain stimulation (DBS) is crucial for treating neurological disorders like Parkinson's disease.
    • Current DBS electrodes face limitations in miniaturization due to material constraints, impacting therapeutic efficacy.
    • Advancements in electrode materials are needed to support smaller, less invasive neuromodulation devices.

    Purpose of the Study:

    • To develop and evaluate an ultra-low impedance platinum-iridium alloy coating for DBS electrodes.
    • To assess the material's performance regarding electrical properties and mechanical robustness.
    • To determine the suitability of the new coating for next-generation DBS systems.

    Main Methods:

    • Five DBS leads were modified with a cost-effective platinum-iridium alloy coating.
    • One lead underwent an insertion test to evaluate mechanical integrity.
    • Four leads were subjected to chronic electrical pulsing for 12 weeks to assess durability.

    Main Results:

    • The platinum-iridium alloy coating significantly enhanced the electrical properties of the DBS electrodes.
    • The coating demonstrated robustness during insertion into brain tissue.
    • The material remained stable and effective after 12 weeks of chronic pulsing.

    Conclusions:

    • The ultra-low impedance platinum-iridium alloy coating offers a viable solution for improving DBS electrode performance.
    • This material advancement supports the development of smaller, less invasive neuromodulation technologies.
    • The enhanced electrodes show promise for future deep brain stimulation therapies.