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A genetic influence on alveolar cell carcinoma
S M Paul1, B Bacharach, C Goepp
1Department of Surgery, Jefferson Medical College, Philadelphia, Pennsylvania.
Journal of Surgical Oncology
|December 1, 1987
Abstract:
Analysis of three siblings with alveolar carcinoma is presented. HLA markers were performed on the index cases and on a normal sibling control. The three affected patients shared HLA-A 28, which was absent in the control sibling. A familial recessive trait may have contributed to the development of alveolar cell carcinoma in this family. This family represents the first reported group of three siblings with alveolar carcinoma.