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Subacute sensory neuronopathy associated with small cell lung carcinoma: diagnosis aided by autoimmune serology
D W Kimmel1, B P O'Neill, V A Lennon
1Department of Neurology, Mayo Clinic, Rochester, MN 55905.
Mayo Clinic Proceedings
|January 1, 1988
Abstract:
In two patients with subacute sensory neuronopathy associated with small cell carcinoma of the lung, the diagnosis of the paraneoplastic syndrome was aided by the finding, in highly diluted serum (1/500 and 1/2,000, respectively), of unusual and distinctive antinuclear antibodies with reactivity restricted to neuronal nuclei. Magnetic resonance imaging of the chest was instrumental in detecting both lung cancers.