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Keratoacanthoma Centrifugum Marginatum: Response to Acitretin
Abdulmohti Hawilo1, Ines Zaraa2,3, Dalenda El Euch1
1Department of Dermatology, La Rabta Hospital Tunis, Tunis, Tunisia.
Skinmed
|March 9, 2017
Summary
A rare keratotic plaque on a 70-year-old woman
Area of Science:
- Dermatology
- Pathology
Background:
- Presents a case of a previously healthy 70-year-old woman.
- Details a 5-month history of an asymptomatic keratotic, papulonodular plaque on the right forearm.
Observation:
- The lesion evolved from a follicular papule with peripheral proliferation.
- Clinical examination revealed an arciform plaque (10x5 cm) with raised, infiltrated borders and central atrophy.
- Yellowish exudate was observed from coalescent nodules on the border.
Findings:
- No history of trauma, chemical exposure, immunosuppression, or neoplasm.
- Systemic physical and laboratory examinations, including X-ray and serologies (HIV, hepatitis, syphilis), were normal, ruling out internal malignancy.
Implications:
- Highlights a unique presentation of a dermatological condition.
- Emphasizes the importance of thorough clinical examination for diagnosing rare skin lesions.
- Suggests further investigation may be needed to determine the exact etiology of this specific plaque.

