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Updated: Mar 6, 2026

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Repetitive Transcranial Magnetic Stimulation to the Unilateral Hemisphere of Rat Brain
Published on: October 22, 2016
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[Repetitive Transcranial Magnetic Stimulation for Intractable Pain]
1Department of Neuromodulation and Neurosurgery, Osaka University Graduate School of Medicine.
Brain and Nerve = Shinkei Kenkyu No Shinpo
|March 9, 2017
Summary
Repetitive transcranial magnetic stimulation (rTMS) offers a non-invasive approach to pain management. Researchers are developing a new system to repeat rTMS treatments for potentially better outcomes in intractable pain.
Area of Science:
- Neuroscience
- Medical Technology
- Pain Management
Background:
- Electrical motor cortex stimulation (EMCS) is an approved pain treatment in Japan but requires craniotomy, deterring some patients.
- Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive alternative, but its effects are temporary with a 20-50% response rate.
Purpose of the Study:
- To develop a convenient system for repeating repetitive transcranial magnetic stimulation (rTMS) treatments.
- To explore the potential of repeated rTMS for managing intractable pain by targeting responders.
Main Methods:
- Development of a new, convenient system for repeating rTMS treatments.
- Initiation of an investigator-initiated trial in December 2015 using the new rTMS machine.
Main Results:
- The study is ongoing, with a trial initiated in December 2015 using a new rTMS system.
- Further results regarding the efficacy and response rates of the new system are pending.
Conclusions:
- A new system for repeated rTMS is under development to improve non-invasive pain management.
- Targeting rTMS responders with repeated treatments may offer a solution for intractable pain.

