Related Experiment Video
Updated: Mar 6, 2026

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
Published on: March 15, 2024
Ischaemic priapism: A clinical review
Joanne Ridgley1, Nicholas Raison2, M Iqbal Sheikh3
1GKT School of Medicine, King's College London, London, UK.
Ischaemic priapism requires immediate intervention to restore blood flow and prevent complications. Treatment involves aspiration, phenylephrine injection, surgical shunting, and potentially penile prosthesis insertion for optimal outcomes.
Area of Science:
- Urology
- Emergency Medicine
- Andrology
Background:
- Ischaemic priapism is a medical emergency characterized by prolonged penile erection with no or minimal blood flow.
- Prompt treatment is crucial to prevent penile necrosis and long-term erectile dysfunction.
Purpose of the Study:
- To review current literature on ischaemic priapism management.
- To identify optimal treatment pathways and areas for guideline improvement.
Main Methods:
- A comprehensive literature search was conducted using PubMed, Ovid, MEDLINE, and the Cochrane Library.
- Key studies concerning the management of ischaemic priapism were identified and analyzed.
Main Results:
- Initial treatment involves aspiration of corporeal blood; irrigation efficacy remains inconclusive.
- Phenylephrine is the recommended sympathomimetic for injection due to its efficacy and safety profile.
- Surgical shunting (distal first) or immediate penile prosthesis insertion are subsequent steps, with inflatable prostheses offering high patient satisfaction.
Conclusions:
- Further research is needed to establish definitive recommendations for irrigation and shunting procedures.
- Optimizing treatment protocols is essential for successful detumescence and preservation of erectile function.
More Related Videos
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Angina III: Clinical Manifestations and Assessment
Aneurysm II: Clinical Manifestations and Diagnostic Studies

