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Updated: Mar 6, 2026
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Modeling the Early Steps of Ovarian Cancer Dissemination in an Organotypic Culture of the Human Peritoneal Cavity
Published on: December 31, 2015
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An exceptional evolution of primary peritoneal serous carcinoma
Wala Ben Kridis1, Syrine Sghaier1, Nabil Toumi1
1a Department of Oncology , Habib Bourguiba Hospital , Sfax , Tunisia.
Acta Clinica Belgica
|March 9, 2017
Summary
Primary peritoneal serous carcinoma (PPSC) is a rare cancer. Brain metastases from PPSC are exceptionally rare, but this case showed a good response to radiotherapy and chemotherapy.
Area of Science:
- Oncology
- Neurosurgery
Background:
- Primary peritoneal serous carcinoma (PPSC) is a rare malignancy.
- PPSC shares clinical and histopathological similarities with serous ovarian papillary carcinoma.
Observation:
- Brain metastases (BM) from PPSC are exceedingly rare.
- This report details a case of BM occurring two years after complete remission of PPSC.
Findings:
- The reported case of PPSC with brain metastases showed a favorable response to treatment.
- Treatment included radiotherapy followed by systemic chemotherapy with Carboplatin and Paclitaxel.
Implications:
- This case highlights the possibility of rare brain metastases from PPSC.
- Increased physician awareness of this rare entity and its treatment response is crucial.
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