Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Structure01:55

Bone Structure

52.4K
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
52.4K
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

3.9K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
3.9K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

4.1K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
4.1K
Compact Bone01:27

Compact Bone

17.8K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
17.8K
Fractures: Bone Repair01:27

Fractures: Bone Repair

6.1K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
6.1K
Bone as Supporting Connective Tissue01:23

Bone as Supporting Connective Tissue

7.7K
Bone tissue forms the internal skeleton of vertebrate animals, providing structure to the body.
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts—...
7.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Intensity Physical Activity During Late Adolescence Predicts Young Adult CT-Based Finite Element Bone Strength in Emerging Adulthood: Iowa Bone Development Study.

Children (Basel, Switzerland)·2025
Same author

Reference Standards for Vertical Jump Power and Handgrip Strength for Screening the Risk of Low Bone and Muscle Mass for Age in Youth.

Journal of strength and conditioning research·2025
Same author

Associations Between Youth Sport Participation and Bone, Muscle, and Fat in Adulthood: Iowa Bone Development Study.

International journal of environmental research and public health·2025
Same author

New Protocol for Submaximal and Peak Exercise Values for Children and Adolescents: The Muscatine Study.

Pediatric exercise science·2024
Same author

Body composition and musculoskeletal fitness: A cluster analysis for the identification of risk phenotypes for pediatric sarcopenia.

Clinical nutrition (Edinburgh, Scotland)·2023
Same author

The Influence of Accelerometer Epoch Length on Associations of Physical Activity Intensity and Volume with Bone Outcomes.

Journal of sports science & medicine·2023

Related Experiment Video

Updated: Mar 6, 2026

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis
08:04

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

Published on: March 11, 2017

9.9K

2016 The Year That Was: Bone Strength.

Kathleen F Janz1

  • 11 University of Iowa.

Pediatric Exercise Science
|March 9, 2017
PubMed
Summary

Physical activity is crucial for building strong bones in children and adolescents. Recent studies explore bone development and how genetics and exercise interact to reduce future fracture risk.

Area of Science:

  • Pediatric bone health
  • Exercise science
  • Genetics and bone metabolism

Background:

  • Physical activity is a key lifestyle factor for optimizing bone strength during childhood and adolescence.
  • Bone health during growth is critical for reducing fracture risk in later life.
  • Understanding bone development is essential for promoting lifelong skeletal wellness.

Purpose of the Study:

  • To highlight significant 2016 research on pediatric bone strength.
  • To examine the comprehensive approach to bone development by Weaver et al.
  • To explore the novel area of genetic-environment interactions in pediatric bone health, as studied by Mitchell et al.

Main Methods:

  • Review of two key 2016 publications on pediatric bone health.
  • Analysis of Weaver et al.'s comprehensive study on bone development.

More Related Videos

Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome
07:16

Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome

Published on: March 4, 2016

17.8K
Cantilever Bending of Murine Femoral Necks
06:44

Cantilever Bending of Murine Femoral Necks

Published on: January 5, 2022

2.5K

Related Experiment Videos

Last Updated: Mar 6, 2026

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis
08:04

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

Published on: March 11, 2017

9.9K
Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome
07:16

Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome

Published on: March 4, 2016

17.8K
Cantilever Bending of Murine Femoral Necks
06:44

Cantilever Bending of Murine Femoral Necks

Published on: January 5, 2022

2.5K
  • Examination of Mitchell et al.'s research on genetic-environment interactions (bone mineral density-lowering alleles and physical activity).

    • Main Results:

    • Physical activity is highly effective in enhancing bone strength during developmental years.
    • Weaver et al. provided a thorough understanding of bone development.
    • Mitchell et al. introduced the concept of gene-environment interplay influencing bone density in youth.

    Conclusions:

    • Optimizing physical activity during growth is vital for establishing robust bone structure.
    • Future research directions include personalized medicine approaches for pediatric bone health.
    • Understanding genetic predispositions alongside lifestyle factors like exercise can inform targeted interventions.