A new method for selective reduction in TRAP sequence with a contraindication to fetoscopic surgery: A case report
Qi Li1, Xin-Hua Wu, Wei-She Zhang
1Department of Obstetrics and Gynecology, Xiang-Ya Hospital, Central South University, Hunan, Changsha, China.
Medicine
|March 9, 2017
Summary
A new method for multifetal pregnancy reduction (MFPR) using hypertonic sodium chloride injection into the umbilical cord offers a safer alternative for monochorionic pregnancies. This technique successfully reduced fetuses in two cases, resulting in healthy infant survival.
Area of Science:
- Maternal-Fetal Medicine
- Reproductive Surgery
- Genetics
Background:
- Traditional multifetal pregnancy reduction (MFPR) using potassium chloride is associated with high miscarriage rates in monochorionic multiple pregnancies (MMPs).
- Radiofrequency ablation and fetoscopic laser surgery are alternatives for selective fetal reduction in MMPs but have contraindications, such as twin reversed arterial perfusion (TRAP) sequence.
- Complicated pregnancies with TRAP sequence, polyhydramnios, or anterior placenta pose challenges for existing MFPR methods.


