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Updated: Mar 6, 2026

Curtain Flow Column: Optimization of Efficiency and Sensitivity
Published on: June 12, 2016
Exploring flow rate selection in HIPEC procedures
Thales Paulo Batista1, Levon Badiglian Filho2, Cristiano Souza Leão1
1Department of Surgery, Pernambucan Health Faculty, Professor Fernando Figueira Institute of Integral Medicine, Recife, Pernambuco, Brazil.
Abstract:
Cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) has emerged as a main comprehensive treatment of peritoneal malignancies. However, current data on the literature are very heterogeneous in terms of its technical particularities, which require some efforts to standardization of practices. In these setting, we present some early data from a pioneering clinical trial in Brazil (ClinicalTrials.gov Identifier: NCT02249013) to explore the dynamic relationships between flow rates and temperature parameters in the first cases of our study, which may help in selecting better technical parameters during HIPEC procedures.
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