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Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid
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Topical treatments for acne.

Marita Kosmadaki1, Andreas Katsambas1

  • 1Andreas Sygros Hospital, 5, University of Athens, Greece, Ionos Dragoumi Street, Athens 11528, Greece.

Clinics in Dermatology
|March 10, 2017
PubMed
Summary
This summary is machine-generated.

This review covers prescription topical acne treatments, including antibiotics, dapsone, benzyl peroxide, azelaic acid, and retinoids. Combining treatments is recommended to improve efficacy and prevent antibiotic resistance.

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Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Topical medications have a long history of successful acne treatment.
  • Acne vulgaris is a common skin condition with various treatment options.

Purpose of the Study:

  • To review the use, efficacy, and safety of prescription topical acne medications.
  • To highlight the benefits of combination therapy for acne management.

Main Methods:

  • Literature review of prescription topical acne treatments.
  • Analysis of efficacy, safety, and resistance patterns.

Main Results:

  • Topical antibiotics should be combined with other agents to prevent resistance.
  • Benzoyl peroxide is effective in preventing bacterial resistance.
  • Topical retinoids target comedonal and inflammatory acne lesions.
  • Azelaic acid treats acne and post-inflammatory hyperpigmentation.

Conclusions:

  • Combination therapy addresses multiple acne pathogenesis aspects, potentially increasing patient benefit.
  • Strategic use of topical agents is crucial for effective acne treatment and resistance prevention.