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Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Related Experiment Video

Updated: Mar 6, 2026

In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin

In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin

Published on: July 3, 2025

Demodex and rosacea revisited.

Ellen M Moran¹, Ruth Foley², Frank C Powell²

¹Education and Research Centre, St. Vincent's University Hospital, Dublin, Ireland.

Clinics in Dermatology

|March 10, 2017

Summary

Demodex mites, common on human skin, may play a role in rosacea. New research explores how these mites interact with the immune system and influence skin health.

Area of Science:

Microbiology
Dermatology
Immunology

Background:

Demodex mites are part of the human skin microbiome.
Their exact role in skin homeostasis and disease is not fully understood.
Ivermectin therapy for rosacea has increased interest in Demodex mites.

Purpose of the Study:

To investigate the role of Demodex mites in the pathogenesis of rosacea.
To understand how Demodex mites modulate the host immune system.

Main Methods:

This study focuses on the interaction between Demodex mites and the human immune system in the context of rosacea.

Main Results:

The precise function of Demodex mites in normal and diseased skin requires further elucidation.

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Last Updated: Mar 6, 2026

In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin

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Published on: July 3, 2025

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases

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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

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The study highlights the potential immunomodulatory capabilities of Demodex mites.

Conclusions:

Demodex mites are implicated in rosacea pathogenesis.
Further research is needed to fully understand Demodex mite interactions with the skin microbiome and immune system.