Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Small-cell bronchogenic carcinoma: CT evaluation.

J L Pearlberg1, M A Sandler, J W Lewis

  • 1Department of Radiology, Henry Ford Hospital, Detroit, MI 48202.

AJR. American Journal of Roentgenology
|February 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current status of infectious diseases among migrants and non-citizens in Malaysia.

Tropical biomedicine·2023
Same author

Helminth parasites of the wood mouse <i>Apodemus sylvaticus</i> in Southern England: levels of infection, species richness and interactions between species.

Journal of helminthology·2023
Same author

A century of the <i>Journal of Helminthology</i>.

Journal of helminthology·2023
Same author

Public health status of Myanmar refugees in South East Asia: A Malaysian case study.

Tropical biomedicine·2022
Same author

Spatial interactions between two nematode species along the intestine of the wood mouse <i>Apodemus sylvaticus</i> from woodland and grassland sites in southern England.

Journal of helminthology·2021
Same author

Post-era mass drug administration: an update on intestinal parasitic infections in urban poor communities in Peninsular Malaysia.

Tropical biomedicine·2021
Same journal

Optimizing and Personalizing PSMA Radiopharmaceutical Selection.

AJR. American journal of roentgenology·2026
Same journal

The Importance of Distinguishing One- and Two-sided Hypothesis Tests.

AJR. American journal of roentgenology·2026
Same journal

Advances in Diabetes Medications and Patient Preparation for Oncologic FDG PET: <i>AJR</i> Expert Panel Narrative Review.

AJR. American journal of roentgenology·2026
Same journal

Incorporating BI-RADS v2025 Into Clinical Reporting.

AJR. American journal of roentgenology·2026
Same journal

Navigating Office Politics: Bullying, Gossip, and Workplace Incivility.

AJR. American journal of roentgenology·2026
Same journal

Author Disclosure of Use of Generative Artificial Intelligence Technologies in Submissions to <i>AJR</i>: Reflections From the <i>AJR</i> Editor in Chief.

AJR. American journal of roentgenology·2026
See all related articles

Computed tomography (CT) reveals widespread mediastinal involvement in 92% of small-cell lung cancer patients before treatment. This study details lymphadenopathy distribution and other intrathoracic findings on CT scans.

Area of Science:

  • Oncology
  • Radiology
  • Pulmonology

Background:

  • Small-cell bronchogenic carcinoma (SCLC) is an aggressive lung cancer subtype.
  • Accurate staging is crucial for treatment planning in SCLC.
  • Conventional radiography has limitations in detecting mediastinal involvement.

Purpose of the Study:

  • To characterize the spectrum of intrathoracic findings on CT scans in patients with untreated small-cell lung cancer.
  • To assess the frequency and distribution of lymphadenopathy in mediastinal compartments.
  • To compare CT findings with conventional radiography for mediastinal staging.

Main Methods:

  • Retrospective review of CT examinations in 37 patients with proven, untreated SCLC.
  • Assessment of lymphadenopathy distribution across American Thoracic Society-designated mediastinal compartments.

Related Experiment Videos

  • Evaluation of additional intrathoracic findings such as pleural effusion and airway compromise.

    • Main Results:

    • Mediastinal involvement detected by CT in 92% of cases, significantly higher than the 13% reported with conventional radiography.
    • High frequencies of lymph node enlargement observed in the right hilum (43%), left hilum (49%), and subcarinal (65%) regions.
    • Common additional findings included pleural effusion (38%), pericardial thickening (38%), and tracheobronchial narrowing (68%).

    Conclusions:

    • CT is highly sensitive for detecting mediastinal involvement in SCLC.
    • The study provides a detailed map of intrathoracic CT findings in untreated SCLC.
    • CT offers a comprehensive assessment of disease extent, aiding in treatment decisions.