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Obesity Increases Risk-Adjusted Morbidity, Mortality, and Cost Following Cardiac Surgery
Ravi K Ghanta1, Damien J LaPar2, Qianzi Zhang3
1Baylor College of Medicine, Houston, TX ghanta@bcm.edu.
Insights
Obesity significantly increases cardiac surgery costs and risks. Higher body mass index (BMI) is linked to greater mortality, complications like renal failure and infections, and increased hospital expenses.
Area of Science:
- Cardiovascular Surgery
- Obesity Medicine
- Health Economics
Background:
- Rising obesity rates present challenges in healthcare.
- Limited data exists on obesity's impact on cardiac surgery costs.
- This study investigates the relationship between body mass index (BMI) and outcomes/costs in cardiac surgery patients.
Purpose of the Study:
- To determine if increasing BMI correlates with adverse risk-adjusted outcomes after cardiac surgery.
- To assess the association between BMI and hospital costs for patients undergoing cardiac procedures.
Main Methods:
- Analysis of 13,637 cardiac surgery patients from a Society of Thoracic Surgeons database.
- Patients categorized by BMI: normal/overweight (18.5-30), obese (30-40), and morbidly obese (>40).
- Outcomes and costs compared across BMI groups and modeled continuously, adjusting for preoperative risk scores.
Main Results:
- Morbidly obese patients had ~60% higher mortality, >2x renal failure, and 6.5x deep sternal wound infections compared to normal weight patients.
- Risk-adjusted analysis confirmed BMI's significant association with mortality (P<0.001) and major morbidity (P<0.001).
- Risk-adjusted hospital costs increased with BMI, with morbidly obese patients incurring 17.2% higher costs.
Conclusions:
- Elevated BMI is independently associated with increased mortality, major morbidity, and healthcare costs following cardiac surgery.
- BMI should be a more significant factor in risk stratification and resource allocation for these patients.
Background:
Despite the epidemic rise in obesity, few studies have evaluated the effect of obesity on cost following cardiac surgery. We hypothesized that increasing body mass index (BMI) is associated with worse risk-adjusted outcomes and higher cost.
Methods And Results:
Medical records for 13 637 consecutive patients who underwent coronary artery bypass grafting (9702), aortic (1535) or mitral (837) valve surgery, and combined valve-coronary artery bypass grafting (1663) procedures were extracted from a regional Society of Thoracic Surgeons certified database. Patients were stratified by BMI: normal to overweight (BMI 18.5-30), obese (BMI 30-40), and morbidly obese (BMI >40). Differences in outcomes and cost were compared between BMI strata and also modeled as a continuous function of BMI with adjustment for preoperative risk using Society of Thoracic Surgeons predictive risk indices. Morbidly obese patients incurred nearly 60% greater observed mortality than normal weight patients. Moreover, morbidly obese patients had greater than 2-fold increase in renal failure and 6.5-fold increase in deep sternal wound infection. After risk adjustment, a significant association was found between BMI and mortality (P<0.001) and major morbidity (P<0.001). The risk-adjusted odds ratio for mortality for morbidly obese patients was 1.57 (P=0.02) compared to normal patients. Importantly, risk-adjusted total hospital cost increased with BMI, with 17.2% higher costs in morbidly obese patients.
Conclusions:
Higher BMI is associated with increased mortality, major morbidity, and cost for hospital care. As such, BMI should be more strongly considered in risk assessment and resource allocation.
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