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Talbot-Lau X-ray phase contrast for tiling-based acquisitions without reference scanning.

Sebastian Kaeppler¹, Maria Seifert², Florian Horn²

¹Pattern Recognition Lab, Friedrich-Alexander-University Erlangen-Nuremberg, Martensstr. 3, 91058, Erlangen, Germany.

Medical Physics

|March 10, 2017

Summary

This study introduces a computational method to eliminate the need for separate phase reference scans in grating-based Talbot-Lau interferometry. This technique simplifies the acquisition of large objects and enhances image quality by mitigating reference phase errors.

Keywords:

grating interferometer phase-contrast reference image x-ray imaging

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Area of Science:

Medical Imaging
X-ray Physics
Computational Imaging

Background:

Grating-based Talbot-Lau interferometers are widely used for phase-contrast X-ray imaging.
Acquisitions require a pre-scan reference, complicating large object imaging due to tiling and potential phase drift.

Purpose of the Study:

To develop an image processing technique that removes the necessity for phase reference scans in tiled acquisitions.
To address the challenges of phase reference drift in large object imaging with Talbot-Lau interferometry.

Main Methods:

A novel image processing technique was developed to estimate phase reference data directly from object scans.
Tailored iterated robust regression with an efficient optimizer was employed for reference estimation.

Main Results:

The computationally estimated reference closely matched acquired references.
The proposed method improved final image quality, likely by reducing errors associated with acquiring physical reference scans.

Conclusions:

Computational estimation of phase reference data offers significant advantages for phase-contrast imaging of large objects.
This approach reduces scanning complexity and enhances overall image quality in X-ray applications.