Two new threitol orsellinates from a sea mud-derived fungus, Ascotricha sp. ZJ-M-5
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Published on: December 2, 2022
Xiu-Mei Xu1,2, Dan-Yi Li2, Hui-Ming Hua1,2
1a Key Laboratory of Structure-based Drug Design & Discovery, Ministry of Education , Shenyang Pharmaceutical University , Shenyang 110016 , China.
Abstract:
Two new d-threitol orsellinates (1-2) were isolated from the EtOAc extract of a sea mud-derived fungus, Ascotricha sp. ZJ-M-5, cultured in Czapek Dox broth. These two compounds featured in the symmetrical substitution of orsellinic acid or acetic acid, which was established on the basis of 1D and 2D NMR experiments. The characteristic optical rotations enabled the assignment of the absolute configuration.

