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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
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Probiotic use in an infectious disease setting.

Gregor Reid1

  • 1a Department of Microbiology and Immunology, Lawson Health Research Institute , University of Western Ontario , London , Canada ​​.

Expert Review of Anti-Infective Therapy
|March 10, 2017
PubMed
Summary

Beneficial microbes, known as probiotics, show promise in managing infectious diseases and combating antimicrobial resistance. Integrating probiotics into mainstream medicine offers hope against escalating infections.

Keywords:
Infectious diseasesLactobacillusantibioticsintensive careprobiotics

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Probiotics

Background:

  • Growing antimicrobial resistance necessitates alternative therapies for infectious diseases.
  • Probiotics represent a potential adjunct or alternative therapeutic strategy.

Purpose of the Study:

  • To review the clinical evidence supporting the use of beneficial microbes (probiotics) in managing infectious diseases.
  • To highlight the potential applications and barriers to the implementation of probiotics in clinical practice.

Main Methods:

  • Literature review of papers published in PubMed.
  • Case presentation on the beneficial role of microbes in infectious disease management.

Main Results:

  • Clinical evidence suggests probiotics can aid in managing necrotizing enterocolitis, surgical infections, antibiotic-associated infections, and urogenital infections.
  • Probiotics may reduce the severity and duration of respiratory infections.

Conclusions:

  • Probiotics offer a hopeful avenue for infectious disease management, especially with rising antibiotic resistance.
  • Overcoming physician and regulatory hesitation is key to integrating probiotics into mainstream healthcare.