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Updated: Mar 6, 2026

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Sleep disruption in chronic rhinosinusitis.

Mahboobeh Mahdavinia1, Robert P Schleimer2, Ali Keshavarzian3

  • 1a Allergy and Immunology Section, Department of Immunology and Microbiology , Rush University Medical Center , Chicago , IL , USA.

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|March 10, 2017
PubMed
Summary

Chronic rhinosinusitis (CRS) significantly disrupts sleep in 60-75% of patients, impacting quality of life. Further research is needed to understand the underlying mechanisms of this widespread sleep disturbance in CRS.

Keywords:
Chronic rhinosinusitis (CRS)infectionrespiratorysleepsleep disruption

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Area of Science:

  • Otolaryngology
  • Sleep Medicine
  • Quality of Life Research

Background:

  • Chronic rhinosinusitis (CRS) is a prevalent upper airway disease affecting quality of life (QOL).
  • Sleep disruption is significantly more common in CRS patients (60-75%) compared to the general population (8-18%).
  • Sleep disruption in CRS is associated with reduced QOL, cognitive impairment, and depression.

Purpose of the Study:

  • To systematically review studies investigating sleep and sleep disturbances in patients with Chronic Rhinosinusitis (CRS).

Main Methods:

  • A systematic literature search was conducted using PubMed/Medline.
  • Studies focusing on sleep and sleep disturbances in CRS patients were assessed.

Main Results:

  • Most CRS patients experience sleep disruption.
  • Key risk factors for sleep disruption in CRS include allergic rhinitis, smoking, and high SNOT-22 scores.
  • The prevalence of sleep-related disordered breathing in CRS is inconsistent in the literature; sleep disruption extends beyond simple nasal obstruction.

Conclusions:

  • Sleep disruption is a major issue in CRS, affecting QOL and functional outcomes.
  • While nasal obstruction is a factor, CRS-related sleep disruption appears multifactorial.
  • There is a significant gap in research understanding the mechanisms behind sleep disruption in CRS.