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A new xanthone from the fungus Apiospora montagnei
Supakorn Arthan1,2, Cholpisut Tantapakul1, Kwanjai Kanokmedhakul1
1a Natural Products Research Unit, Faculty of Science, Department of Chemistry and Center of Excellence for Innovation in Chemistry , Khon Kaen University , Bangkok , Thailand.
Abstract:
A new xanthone derivative, methyl 8-hydroxy-3-hydroxymethylxanthone-1-carboxylate (1), and seven known compounds, 8-hydroxy-3-methylxanthone-1-carboxylate (2), methyl 8-hydroxy-6-methylxanthone-1-carboxylate (3), ergosterol (4), cyathisterone (5), ergosta-4,6,8(14),22-tetraen-3-one (6), calvasterone (7) and 2-hexyl-3-methylmaleic anhydride (8) were first isolated from the fungus Apiospora montagnei. Their structures were elucidated on the basis of spectroscopic analysis (UV, IR, MS, 1D, and 2D NMR). Compounds 5 and 6 showed weak to very weak cytotoxicity against cancer cell lines, NCI-H187 and KB.
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Fungal Group Zygomycota
Fungal Phylum Microsporidia
Fungal Phylum Ascomycota
Antifungal Agents
