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Updated: Mar 6, 2026
Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
Published on: July 27, 2018
[Detecting and measuring functional and organic disease in general population: Development and validation of TOPYPS
Guillem Pailhez1, Juan Castaño2, Silvia Rosado2
1Instituto de Neuropsiquiatría y Adicciones, Hospital del Mar, Barcelona, España; Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, España.
Objective:
To develop and validate the TOPYPS scale, an instrument designed to: (i)detect with a high degree of suspicion the most frequent functional pathologies according to standard diagnostic criteria, and (ii)to assess the physical health in the general population quickly, comprehensive and reliable.
Design:
Validation of a scale.
Location:
Primary Care Centre, Barcelona.
Participants:
The scale was administered to 67 randomly selected adults.
Measurements:
TOPYPS scale was administered to 67 adults randomly selected from a primary care setting in Barcelona, Spain. TOPYPS has six sections based on body systems, each one scored according to the degree of interference in daily activity, type of treatment received, and prognostic of the reported illnesses in each section. Test-retest reliability completions were on two separate occasions one week apart. Validity was then tested by comparing the results with the clinical examination conducted by two different specialists in general practice (gold standard).
Results:
Repeatability (test-retest) and inter-rater agreement for each of the six sections and for the total score were satisfactory. Validity was acceptable both for content and construct, according to their correlation with the gold standard.
Conclusions:
TOPYPS displayed good psychometrical properties. It is a suitable tool to detect and measure functional and organic diseases in general population.
