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Transcription Factor T-bet Orchestrates Lineage Development and Function in the Immune System

Axel Kallies1, Kim L Good-Jacobson2

  • 1Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia.

Trends in Immunology
|March 11, 2017
PubMed
Summary

T-bet is a crucial transcription factor for multiple immune cell types, not just T helper 1 cells. It orchestrates the development and function of effector and memory lymphocytes for effective immunity.

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