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Preliminary development of the Medication Nonpersistence Scale.

Amod S Athavale, John P Bentley, Benjamin F Banahan

    Journal of the American Pharmacists Association : Japha
    |March 11, 2017
    PubMed
    Summary

    A new scale, the Medication Nonpersistence Scale (MNPS), accurately measures patient medication persistence. This self-reported tool aids clinical practice and research by identifying nonpersistent individuals.

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    Area of Science:

    • Health Services Research
    • Psychometrics
    • Pharmaceutical Sciences

    Background:

    • Medication nonpersistence is a significant issue in healthcare.
    • Accurate measurement of medication persistence is crucial for effective interventions.

    Purpose of the Study:

    • To develop and validate the Medication Nonpersistence Scale (MNPS).
    • To create a multi-item, self-reported measure for assessing medication persistence.

    Main Methods:

    • Developed the MNPS, a self-reported scale.
    • Collected data from 675 patients across 3 community pharmacies.
    • Utilized confirmatory factor analysis (CFA) to assess scale structure.
    • Evaluated scale reliability and validity against prescription fill data.

    Main Results:

    • CFA confirmed a single-factor solution with good model fit.
    • The MNPS demonstrated strong reliability and validity (Cronbach alpha = 0.75).
    • A cutoff score of 1 or higher on the MNPS identified nonpersistent patients.

    Conclusions:

    • The MNPS is a psychometrically sound tool for measuring medication persistence.
    • The scale is suitable for use in clinical practice and research settings.
    • The MNPS provides a valuable method for assessing medication adherence.