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Molecular characterization of classical swine fever virus isolates from India during 2012-14
Elina Khatoon1, Nagendra N Barman2, Manab Deka3
1Department of Biotechnology, Gauhati University, Assam 781014, India; Department of Microbiology, College of Veterinary Science, Khanapara, Assam 781022, India.
Abstract:
Classical swine fever is a highly contagious and economically important viral disease of pigs. Outbreaks of classical swine fever virus (CSFV) were recorded in different places in the Kamrup district of Assam in India between the years 2012 and 2014. The nucleotide sequences of the 10 CSFV isolates were analyzed based on the partial nucleotide sequences of the E2, 5'NTR and NS5B genes. Phylogenetic analysis indicated the dominance of subgroup 2.2 along with 2.1 strains in the northeast part of India. Variation in the nucleotide sequences of E2, 5'NTR and 3'NS5B genes of CSFV allows tracking changes in the virus population over time. The study will provide epidemiological information useful for assessing CSFV circulating genogroups in India.
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